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Why take spermidine (Why is spermidine good for you?) 

  • Writer: Shonice Pooniwala
    Shonice Pooniwala
  • Nov 14, 2025
  • 1 min read

Why take spermidine (Why is spermidine good for you?)


In essence, spermidine impacts longevity. Compared to other rodents, naked mole rats live 10-20 years longer, living for a long time without visual aging signs (Greger, 2023, p. 29). This animal has also shown to have high levels of spermidine throughout their life, as found in human centenarians (Greger, 2023, p. 29). 


To answer this question let’s look at the science of aging. There are multiple different pathways to aging (Greger, 2023, p. 11). Autophagy is an important process to be aware of, as are the enzymes Mammalian targets of rapamycin (mTOR) and AMP-activated protein kinase (AMPK) are two enzymes that play a crucial role (Greger, 2023, pp. 14, 101, 25).


 
 
 

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